4.3.2 Using original specie Gene.name

In this section, integration analysis are done without conversion to human ortholog. Conversion from mouse to rat or vice-versa is irrelevant because Gene.name are mostly shared, and when they are not, there is no ortholog available for conversion.

4.3.2.1 Mouse Fluoxetine VS Control for Stressed in Dentate Gyrus

This section corresponds to the first meta-analysis requested by El Chérif.

Table 4.8: Mapping between ids and designs used in the integration plots below
id design
1-GSE43261 GSE43261-FluoxetineResponderVsControl
2-GSE84185 GSE84185-FluoxetineVsControlForStressedResponderInDentateGyrus
3-SRP057486 SRP057486-FluoxetineVsVehicleForBrainCA1StressedSubset
4-Surget2009 Surget2009-FluoxetineVsSalineForStressedInDentateGyrus
Alphabetically-sorted genes significant in at least one comparison (p-value < 0.05 and pvalue rank < 301). + and – signs highlight respectively upregulated and downregulated genes (|logFoldChange| > 0.1 and raw pvalue < 0.05).

Figure 4.96: Alphabetically-sorted genes significant in at least one comparison (p-value < 0.05 and pvalue rank < 301). + and – signs highlight respectively upregulated and downregulated genes (|logFoldChange| > 0.1 and raw pvalue < 0.05).

The xlsx table with all genes is available here

Consensus-sorted genes significant in at least one comparison (p-value < 0.05 and p-value rank < 301). + and – signs highlight respectively upregulated and downregulated genes (|logFoldChange| > 0.1 and raw pvalue < 0.05). Underlying table is available [here](xlsx/resultsIntegrationOriginalSpecieMouseFluoxetineVsControlForStressedConsensus.xlsx)

Figure 4.97: Consensus-sorted genes significant in at least one comparison (p-value < 0.05 and p-value rank < 301). + and – signs highlight respectively upregulated and downregulated genes (|logFoldChange| > 0.1 and raw pvalue < 0.05). Underlying table is available here