4.3.1 To closest human ortholog

4.3.1.1 Mouse Fluoxetine VS Control for Stressed in Dentate Gyrus

This section corresponds to the first meta-analysis requested by El Chérif.

Table 4.1: Mapping between ids and designs used in the integration plots below
id design
1-GSE43261 GSE43261-FluoxetineResponderVsControl
2-GSE84185 GSE84185-FluoxetineVsControlForStressedResponderInDentateGyrus
3-GSE84185 GSE84185-StressedFluoxetineVsStressedAloneInDentateGyrus
4-SRP057486 SRP057486-FluoxetineVsVehicleForBrainCA1StressedSubset
5-Surget2009 Surget2009-FluoxetineVsSalineForStressedInDentateGyrus
Alphabetically-sorted genes significant in at least one comparison (padj < 0.05). + and – signs highlight respectively upregulated and downregulated genes (|logFoldChange| > 0.1 and raw pvalue < 0.05).

Figure 4.75: Alphabetically-sorted genes significant in at least one comparison (padj < 0.05). + and – signs highlight respectively upregulated and downregulated genes (|logFoldChange| > 0.1 and raw pvalue < 0.05).

Consensus-sorted genes significant in at least one comparison (padj < 0.05). + and – signs highlight respectively upregulated and downregulated genes (|logFoldChange| > 0.1 and raw pvalue < 0.05).

Figure 4.76: Consensus-sorted genes significant in at least one comparison (padj < 0.05). + and – signs highlight respectively upregulated and downregulated genes (|logFoldChange| > 0.1 and raw pvalue < 0.05).

Consensus-sorted genes significant in at least one comparison (padj < 0.0001). + and – signs highlight respectively upregulated and downregulated genes (|logFoldChange| > 0.1 and raw pvalue < 0.05). Underlying table is available [here](xlsx/resultsIntegrationMouseFluoxetineVsControlForStressedConsensusPadj0p0001.xlsx)

Figure 4.77: Consensus-sorted genes significant in at least one comparison (padj < 0.0001). + and – signs highlight respectively upregulated and downregulated genes (|logFoldChange| > 0.1 and raw pvalue < 0.05). Underlying table is available here